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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Pentapeptide repeat ： ウィキペディア英語版 Pentapeptide repeat Pentapeptide repeats are a family of sequence motifs found in multiple tandem copies in protein molecules. Pentapeptide repeat proteins are found in all species, but they are found in many copies in cyanobacterial genomes. The repeats were first identified by Black and colleagues in the hglK protein. The later Bateman ''et al.'' showed that a large family of related pentapeptide repeat proteins existed.〔 The function of these repeats is uncertain in most proteins. However, in the MfpA protein a DNA gyrase inhibitor it has been suggested that the pentapeptide repeat structure mimics the structure of DNA. The repeats form a regular right handed four sided beta helix structure known as the Rfr-fold. ==Sequence features== The pentapeptide repeat is a feature seen in protein sequence. It can be approximately described using the 1-letter amino acid code as A(D/N)LXX, where X can be any amino acid . This repeating sequence can be seen in multiple sequence alignments and dot plots of proteins such as HglK. The central position in the pentapeptide repeat is usually a leucine and has been designated as position ''i''. The two previous positions are known as ''i''-1 and ''i''-2. Position i-2 is usually an alanine. The two subsequent positions are denoted ''i''+1 and ''i''+2. The side chains of positions ''i''-2 and ''i'' point into the hydrophobic interior of the protein while the side chains of positions ''i''-1, ''i''+1 and ''i''+2 are exposed on the surface of the proteins. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Pentapeptide repeat」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.